Two of Congress’ staunchest conservatives repelled more centrist challengers to lock up Republican nominations on Tuesday.

For some female incumbents running for reelection in Congress this year, holding their seats comes with a new challenge.

But some challengers lost, and their overall wins were a modest number compared with the 535 House and Senate members. Kessler wasn't impressed with the three progressive challengers who defeated Democratic incumbents, either. Other high-profile progressive hopefuls lost Senate Democratic primaries in Colorado, Kentucky, Maine and Texas, and House contests in states including Georgia, New York and Ohio. Jamaal Bowman, a Black educator raised by a single mom, defeated House Foreign Affairs Committee Chairman Eliot Engel of the Bronx and Westchester, New York. They're an effective and well-funded operation now," said Sean McElwee, who does polling and research for progressive Democrats.

FILE - In this Feb. 25, 2020 file photo, Democratic presidential candidates, Sen. Bernie Sanders, I-Vt., left, and former Vice President Joe Biden, talk before a Democratic presidential primary debate in Charleston, S.C. Sanders, who will speak at the Democratic National Convention Monday, was the last primary challenger standing against Biden. He retains the partys largest cohesive constituency in a progressive base unwavering in its support. Most importantly, young people in this country, whether theyre Black or white or Latino, Native American, Asian American, young people strongly support the progressive agenda.The progressive movement is still far from the driving force of the Democratic Party. One example is Alexandria Ocasio-Cortez, who will help nominate Sanders at the convention and is widely seen as his successor in leading progressives.

FILE - In this March 6, 2020 file photo, Rep. Rashida Tlaib, D-Mich., speaks at a campaign rally in Detroit. Her opponent in the primary was Detroit City Council President Brenda Jones. Y'all, we about to change the world.Beyond signaling momentum, the victories are giving progressives confidence about two upcoming tests. Next week, squad member Rep. Ilhan Omar of Minnesota will face a challenge from a well-funded opponent, Antone Melton-Meaux. In March, Marie Newman knocked off Illinois Rep. Dan Lipinski, an abortion opponent who compared progressive Democrats to a tea party of the left."

WASHINGTON Rep. Alexandria Ocasio-Cortez has endorsed the Democratic primary challenger of a veteran House committee chairman whose New York district is adjacent to her own, the progressive freshman's latest challenge to party leaders. That meant Ocasio-Cortez was trying to topple fellow Democratic Rep. Eliot Engel, 73, chairman of the House Foreign Affairs Committee. Engel is in his 16th House term and represents a district from parts of the Bronx and Westchester, next door to Ocasio-Cortez' home base of the Bronx and Queens. She called Bowman, who is African American, a profound community leader. Engel's district has mostly black and Hispanic voters. Ocasio-Cortezs move also meant she was defying House Democratic leaders, who have stood behind party incumbents facing primary challengers.

WASHINGTON WASHINGTON (AP) Rep. Alexandria Ocasio-Cortez has endorsed the Democratic primary challenger of a veteran House committee chairman and fellow New Yorker in her latest challenge to party leaders. Ocasio-Cortez's support for Bowman puts her in direct opposition to House Speaker Nancy Pelosi, who as a party leader backs incumbents when they face primary foes. This moment requires renewed and revitalized leadership across the country AND at the ballot box, Ocasio-Cortez, 30, tweeted as she lent her support to Bowman. She called Bowman, who is African American, a profound community leader. The solidly Democratic district represented by Engel, who is white, has mostly black and Hispanic voters. Marie Newman defeated Rep. Daniel Lipinski in an Illinois district south of Chicago, but Jessica Cisneros lost to Rep. Henry Cuellar in south Texas.