Josh Allen and the Buffalo Bills head to New England looking for their first division win of the season.

Christian McCaffrey ran for the go-ahead touchdown with 7:54 to play, and the San Francisco 49ers beat the Los Angeles Chargers 22-16 in their first game back from a bye week.

Can we finally start Tony Pollard.

Justin Herbert threw for 340 yards and two touchdowns and Austin Ekeler scored three times as the Los Angeles Chargers built a big early lead and held on for a 34-24 win over the Houston Texans.

Patrick Mahomes threw two touchdown passes, rookie Jaylen Watson returned an interception 99 yards for the go-ahead fourth-quarter score, and the Kansas City Chiefs held on to beat the Los Angeles Chargers 27-24.

The NFL has updated its protocols in reaction to an increase in COVID-19 cases around the league, and it is pushing booster shots as the most effective protection against the coronavirus.

Russell Wilson played his best game since returning from finger surgery by throwing for 231 yards and two touchdowns and the Seattle Seahawks made a late goal line stand to beat the San Francisco 49ers 30-23.

Free agency feels a lot like recruiting to new Jaguars coach Urban Meyer. It certainly should help that the Jaguars have more salary cap space (nearly $73 million) than any other team. (AP Photo/Jay LaPrete, File)JACKSONVILLE, Fla. – Free agency feels a lot like recruiting to new Jaguars coach Urban Meyer. Clemson star Trevor Lawrence is the presumptive choice, and the Jaguars will use free agency to build around him. “That’s a room that’s going to have to be rebuilt in some ways,” said Meyer, who could sign Hunter Henry, Jonnu Smith or Gerald Everett when free agency officially begins Wednesday.

After 51 weeks and 13 games without a win, the Jets finally earned the chance to celebrate with pride. The Jets (1-13) knew their 23-20 victory over the embarrassed Los Angeles Rams on Sunday was never pretty. Moments later, Darnold hit Gore with the short pass over the middle that allowed the Jets to run out the clock. It was an amazing feeling.”With two games left, New York might have ruined its chances at the No. Of the nine teams in NFL history to start 0-13, the Jets were the fourth to win in Week 15.

Josh Reynolds and Gerald Everett caught touchdown passes from Jared Goff, and the Rams won a matchup of dominant defenses, beating the Bears 24-10 on Monday night. “We proved that we were the better defense today,” Floyd said after a six-tackle performance in his first game against Chicago since the Bears released him last offseason. After his first sack, Floyd jumped up and went toward the Bears sideline, shouting and gesticulating at the team that let him go. We’re just one tight unit right now.”The Rams led 10-3 at halftime after holding the Bears to 126 yards. ... TE Tyler Higbee was inactive with a hand injury, missing his second game since 2016.

Jared Goff hit Cooper Kupp for a 55-yard touchdown with 6:56 to play, and the Rams grinded out a 17-9 victory over New York on Sunday before the wild fight between Ramsey and Tate. Los Angeles managed 240 total yards and went nearly 45 minutes between its two touchdowns, but it was enough. Williams said he recognized the Giants' play call from earlier in the game, allowing him to anticipate the throw. Graham Gano kicked three field goals in the Giants’ first game in the Los Angeles area since 1994. Los Angeles had racked up at least 400 total yards in each of its first three games.

(AP Photo/Tony Avelar)The Latest on Week 4 in the NFL (all times EDT)___8:35 p.m.Carson Wentz has thrown his NFL-worst seventh interception of the season for the Philadelphia Eagles. ___7:05 p.m.Bills quarterback Josh Allen’s 1-yard sneak that gave Buffalo a 23-16 lead over Las Vegas early in the fourth quarter. ___7:20 p.m.Buffalo Bills quarterback Josh Allen is back guiding the Bills offense after injuring his left shoulder late in the first half at Las Vegas. ___6:40 p.m.Buffalo Bills quarterback Josh Allen headed to the locker room after falling on his left wrist. The high-scoring start to the 2020 NFL season continued Sunday with several games featuring lots of points and very little defense.

Dak Prescott passed for 266 yards and a touchdown, but Dallas managed three points on its six drives in the second half. The opening of Rams owner Stan Kroenke's $5 billion stadium project was a historic night for the Los Angeles area, albeit one that should have been much more festive. Elliott tied it early in the second quarter with a 19-yard TD catch during which he ran through most of the Los Angeles defense. Van Jefferson's first career reception was a beautiful 31-yard grab in the second quarter, but it was the promising Rams rookie's only reception. Right tackle Cam Erving and tight end Blake Jarwin both didn't return from knee injuries in the second quarter.